N-Isopropylacrylamide-based Temperature-Responsive Polymer with Carboxyl Groups for Controlled Drug Release
نویسندگان
چکیده
منابع مشابه
Preparation and Investigation of Poly (N-isopropylacrylamide-acrylamide) Membranes in Temperature Responsive Drug Delivery
Objective(s) Physiological changes in the body may be utilized as potential triggers for controlled drug delivery. Based on these mechanisms, stimulus-responsive drug delivery has been developed. Materials and Methods In this study, a kind of poly (N-isopropylacrylamide-acrylamide) membrane was prepared by radical copolymerization. Changes in swelling ratios and diameters of the membrane wer...
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A series of semi-interpenetrating, polymer network (semi-IPN), hydrogel beads, composed of calcium alginate (Ca-alginate) and poly(N-isopropylacrylamide) (PNIPAAM), were prepared for a pH/temperature-sensitive drug delivery study. The equilibrium swelling showed the independent pH- and thermo- responsive nature of the developed materials. At pH=2.1, the release amount of indomethacin incorporat...
متن کاملpreparation and investigation of poly (n-isopropylacrylamide-acrylamide) membranes in temperature responsive drug delivery
objective(s) physiological changes in the body may be utilized as potential triggers for controlled drug delivery. based on these mechanisms, stimulus-responsive drug delivery has been developed. materials and methods in this study, a kind of poly (n-isopropylacrylamide-acrylamide) membrane was prepared by radical copolymerization. changes in swelling ratios and diameters of the membrane were i...
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Hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. The present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on pH-sensitive polymers such as poly (acrylic acid). Poly (acrylic acid), p(AA), hydrogel has been synthesized by radical po...
متن کاملChitosan coated alginate beads containing poly(N-isopropylacrylamide) for dual-stimuli-responsive drug release.
Chitosan coated alginate beads containing poly(N-isopropylacrylamide) (PNIPAAM), were prepared to be used as a controlled pH/temperature sensitive drug delivery system with improved encapsulation efficiency and delayed release rate. The studied beads were characterized by differential scanning calorimetry, scanning electron microscopy, and Fourier transform infrared spectroscopy. Water uptake a...
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ژورنال
عنوان ژورنال: Journal of Photopolymer Science and Technology
سال: 2005
ISSN: 0914-9244,1349-6336
DOI: 10.2494/photopolymer.18.515